Background Today, no specific test for the diagnosis of multiple sclerosis (MS) is available
due to the lack of characteristic symptoms at beginning. This circumstance also complicates
estimation of disease progression. Recent findings provided evidence for early, non-lesional
cerebellar damage in patients with (clinically definite) relapsing-remitting MS. Objective To
investigate if microstructural cerebellar alterations can also serve as early structural
biomarker for disease progression and conversion from clinically isolated syndrome (CIS) to …